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Permanent link (DOI): https://doi.org/10.7939/R3B27PZ1M

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The Association Between Physical Activity and Carotid Intima-Media Thickness in Children Open Access

Descriptions

Other title
Subject/Keyword
adiposity
fitness
atherosclerosis
carotid intima-media thickness
physical activity
cardiovascular disease
epidemiology
children
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Darvesh, Nazia
Supervisor and department
Senthilselvan, Ambikaipakan (Public Health Sciences)
Maximova, Katerina (Public Health Sciences)
Examining committee member and department
Voaklander, Don (Public Health Sciences)
Chaput, Jean-Philippe (Pediatrics, University of Ottawa)
Boulé, Normand (Physical Education & Recreation)
Department
Department of Public Health Sciences
Specialization
Epidemiology
Date accepted
2014-01-07T15:19:54Z
Graduation date
2014-06
Degree
Master of Science
Degree level
Master's
Abstract
Modifiable cardiovascular disease (CVD) risk factors, such as adiposity, are already associated with atherosclerotic progression in childhood. Less is known about whether physical activity (PA) is associated with progression of atherosclerosis in non-clinical samples of children. This cross-sectional study used baseline data from 426 eight- to ten-year-olds from the Quebec Adiposity and Lifestyle Investigation in Youth (QUALITY) Study to assess associations between PA and carotid intima media-thickness (cIMT) – a surrogate marker of atherosclerosis, and potential effect modification by adiposity and fitness. Results of this thesis should be interpreted with caution, as validity of cIMT measurement from the QUALITY Study is currently being investigated because of suboptimal reliability and precision of ultrasound equipment. PA was not associated with cIMT in this at-risk sample. Analyses in adiposity or fitness categories showed potential differences by groups. More structured and high-intensity PA may be required to slow atherosclerotic progression between childhood and adulthood.
Language
English
DOI
doi:10.7939/R3B27PZ1M
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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