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Permanent link (DOI): https://doi.org/10.7939/R3J05Q

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Environmental Exposures, Helicobacter pylori Infection and Gastritis in Canadian Arctic Communities Open Access

Descriptions

Other title
Subject/Keyword
Transmission
Helicobacter pylori
Gastritis
Environmental Exposures
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Hastings, Emily V
Supervisor and department
Goodman, Karen J (Medicine and Public Health)
Examining committee member and department
Teshima, Christopher (Medicine)
Hanington, Patrick (Public Health)
Yasui, Yutaka (Public Health)
Department
School of Public Health Sciences
Specialization
Epidemiology
Date accepted
2013-04-02T14:20:02Z
Graduation date
2013-06
Degree
Master of Science
Degree level
Master's
Abstract
The role of environmental exposures in the acquisition of H.pylori and related disease is not yet understood. This analysis examined two hypotheses regarding how environmental exposures may affect digestive health in northern Canada. First, environmental sources of biological contamination may facilitate transmission of H.pylori. Second, exposure to environmental sources of chemical contamination may influence the development of severe gastritis. Data from three northern Canadian communities were used to examine relationships between environmental exposures and digestive health. Using logistic regression, odds ratios and 95% confidence intervals were estimated for the effect of investigated exposures on prevalence of H.pylori and severe gastritis. Findings showed a positive association between exposure to mice and prevalent H.pylori infection. Other zoonotic and waterborne exposures did not appear associated with this infection in the study populations. This analysis also provided evidence of a possible link between untreated water consumption and prevalence of severe gastritis.
Language
English
DOI
doi:10.7939/R3J05Q
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
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File title: Microsoft Word - Hastings, Emily V. MSc Thesis 2013.docx
File author: Emily Hastings
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