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Permanent link (DOI): https://doi.org/10.7939/R3M61BW8J

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Effect of Electrostatic Charge on the Deposition of Monodisperse Uniformly Charged Particles in Idealized Extrathoracic Airway of an Adult, Child and Infant Open Access

Descriptions

Other title
Subject/Keyword
Extrathoracic airway
Electrostatic charge
Particle deposition
Type of item
Thesis
Degree grantor
University of Alberta
Author or creator
Azhdarzadeh, Mehdi
Supervisor and department
Finlay, Warren H.
Examining committee member and department
Olfert, Jason S. (Mechanical Engineering)
Matida, Edgar A. (Mechanical and Aerospace Engineering, Carleton University)
Martin, Andrew (Mechanical Engineering)
Finlay, Warren H. (Mechanical Engineering)
Vehring, Reinhard (Mechanical Engineering)
Department
Department of Mechanical Engineering
Specialization

Date accepted
2014-07-22T13:12:40Z
Graduation date
2014-11
Degree
Doctor of Philosophy
Degree level
Doctoral
Abstract
An in vitro study was performed on the effect of electrostatic charge on the deposition of monodisperse uniformly charged particles in the extrathoracic airway. An atomizer was designed and prototyped to generate particles using controlled Plateau-Rayleigh breakup, and charge via induction. Experiments were conducted in three phases for adult oral-extrathoracic, child oral-extrathoracic (children aged 6-14 years), and infant nasal-extrathoracic (infants aged 3-18 months) airways. For the adult case, the Alberta idealized mouth-throat was used to mimic the oral-extrathoracic airway. Experiments covered particles with aerodynamic diameters of 3-6 μm, at flow rates of 15-30 L/min and charge per particle range of 0-25,000 e. Tests for the deposition of particles in the child oral-extrathoracic airway were conducted using the Alberta idealized child mouth-throat and particles having aerodynamic diameters of 3-6 μm. Volume flow rate of inhaled gas was set to 10-20 L/min and charge of particles was in the range of 0-10,000 e per particle. The Alberta idealized infant nose-throat model was utilized for the infant case, while aerodynamic diameters of particles were 3-6 μm at flow rates of 7.5-15 L/min and the charge level of particles varying between 0-10,000 e/particle. The conductive version of the replicas was utilized to avoid any repulsion between the charge of the particles accumulated on the internal walls of the airway and the aerosol particles passing through the airway. For each case, nonlinear least squares minimization was used to develop a different empirical equation, including electrostatic effects for predicting the deposition of particles in the airway.
Language
English
DOI
doi:10.7939/R3M61BW8J
Rights
Permission is hereby granted to the University of Alberta Libraries to reproduce single copies of this thesis and to lend or sell such copies for private, scholarly or scientific research purposes only. Where the thesis is converted to, or otherwise made available in digital form, the University of Alberta will advise potential users of the thesis of these terms. The author reserves all other publication and other rights in association with the copyright in the thesis and, except as herein before provided, neither the thesis nor any substantial portion thereof may be printed or otherwise reproduced in any material form whatsoever without the author's prior written permission.
Citation for previous publication
Azhdarzadeh, M., Olfert, J. S., Vehring, R., Finlay, W. H. (2014). Effect of Electrostatic Charge on Oral-Extrathoracic Deposition for Uniformly Charged Monodisperse Aerosols. Journal of Aerosol Science, 68, 38-45. DOI: 10.1016/j.jaerosci.2013.11.002  http://www.sciencedirect.com/science/article/pii/S002185021300222XAzhdarzadeh
, M., Olfert, J. S., Vehring, R., Finlay, W. H. (2014). Effect of Induced Charge on Deposition of Uniformly Charged Particles in a Pediatric Oral-extrathoracic Airway. Aerosol Science and Technology, 48:508-514. DOI:10.1080/02786826.2014.896989  http://www.tandfonline.com/doi/full/10.1080/02786826.2014.896989#.U82SnbHLNLMAzhdarzadeh
, M., Olfert, J. S., Vehring, R., Finlay, W. H. (2014). Effect of electrostatic charge on deposition of uniformly charged monodisperse particles in the nasal-extrathoracic airways of an infant. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 27:1-5. doi:10.1089/jamp.2013.1118  http://online.liebertpub.com/doi/abs/10.1089/jamp.2013.1118

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