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Journal Articles (Chemistry)
Items in this Collection
- 2Autoimmune-Disease
- 1Carbohydrate Antigen
- 1Cd22
- 1Donor-Specific Transfusion
- 1Family-Member Bim
- 1Hemophilia-A; In-Vivo
- 1Gale, Andrew J.
- 1Macauley, M. S.
- 1Macauley, Matthew S.
- 1Nycholat, Corwin M.
- 1Paulson, J. C.
- 1Paulson, James C.
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2013
Pfrengle, Fabian, Paulson, James C., Gale, Andrew J., Nycholat, Corwin M., von Drygalski, Annette, Rademacher, Christoph, Macauley, Matthew S.
Antibodies confer humoral immunity but can also be harmful when they target an autoantigen, alloantigen, allergen, or biotherapeutic. New strategies are needed for antigen-specific suppression of undesired antibody responses, particularly to T cell–dependent protein antigens, because they elicit...
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Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells
2014
Paulson, J. C. , Macauley, M. S.
Infusion of blood cells from a donor can induce humoral tolerance in a recipient and increase the probability of successful organ transplant, a clinical method defined as donor-specific transfusion (DST). Despite the clinical success of DST, the immunological mechanisms by which blood cells...