Journal Articles (Agricultural, Food and Nutritional Science)
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- 1Baracos, Vickie
- 1Dieleman, Levinus
- 1Farhangfar, Arazm
- 1Gänzle, Michael G.
- 1Lin, Xiaoxi B.
- 1Sawyer, Michael B.
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The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...
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