ERA

Complementary and Alternative Research and Education (CARE)

Complementary and Alternative Research and Education (CARE), launched in 2003 at the Department of Pediatrics at the University of Alberta, is Canada’s first academic pediatric integrative medicine program. Its mission is to generate and disseminate evidence about pediatric complementary and alternative medicine (CAM), to ensure safe and informed use. A clinical assessment program was added in 2006.
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  1. Primary Outcomes Reporting in Trials (PORTal): a systematic review of inadequate reporting in pediatric randomized controlled trials [Download]

    Title: Primary Outcomes Reporting in Trials (PORTal): a systematic review of inadequate reporting in pediatric randomized controlled trials
    Creator: Bhaloo, Zafira
    Description: Objective: Conduct a systematic review of pediatric randomized controlled trials published in high impact journals to assess the reporting of primary outcomes and the psychometric properties of their measures. Study Design and Setting: Systematic review with screening and simultaneous data extraction conducted by two independent reviewers. Electronic searches of six general medicine and four pediatric journals were conducted in MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL) databases. Randomized controlled trials of a single phase/step in a single publication, published in English between 2000 and 2010 with participants less than 21 years of age were included. Results: A random sample of 20% (n=446) of 2229 initial references was screened and 206 (46%) met inclusion criteria. Half (48.5%) of included studies reported a singular primary outcome, 27% did not identify any primary outcome, and 24% identified multiple primary outcomes (range 2-20). Twenty one trials used an instrument to measure their primary outcome, but only 7 (33%) reported its psychometric properties. Conclusions: Pediatric trials published in top medical journals have inadequate reporting of their primary outcomes and the psychometric properties of their outcome measures. Whether the issue is one of poor reporting and/or poor validation will be further investigated.
    Subjects: Pediatric, Outcome measure, Primary outcome, Reporting, Systematic review, Randomized controlled trial
    Date Created: 2016/09/22
  2. Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome [Download]

    Title: Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome
    Creator: Adams D
    Subjects: Fatigue Syndrome, Chronic, Fatigue, Drugs, Chinese Herbal, Chronic Disease
    Date Created: 2009
  3. Interventions to prevent hypothermia at birth in preterm and/or low birthweight infants [Download]

    Title: Interventions to prevent hypothermia at birth in preterm and/or low birthweight infants
    Creator: McCall EM
    Subjects: Perinatal Care, Hypothermia, Randomized Controlled Trials as Topic, Infant, Premature, Diseases, Infant, Premature, Infant, Newborn, Infant, Low Birth Weight
    Date Created: 2010
  4. Antioxidant micronutrients for lung disease in cystic fibrosis [Download]

    Title: Antioxidant micronutrients for lung disease in cystic fibrosis
    Creator: Shamseer L
    Subjects: Vitamin E, Selenium, Ascorbic Acid, Quality of Life, Randomized Controlled Trials as Topic, Cystic Fibrosis, Oxidative Stress, Antioxidants, Vitamins, Micronutrients
    Date Created: 2010